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Test Code VITK1 Vitamin K1, Serum

Useful For

Assessing circulating vitamin K1 concentration

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Vitamin K1, S

Specimen Type

Serum


Specimen Required


Patient Preparation: Fasting overnight (12-14 hours) (infants-collect prior to next feeding).

Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.75 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 30 days
  Ambient  30 days
  Frozen  30 days

Reference Values

<18 years: Not established

≥18 years: 0.10-2.20 ng/mL

Interpretation

Low vitamin K1 concentrations in the serum are indicative of insufficiency and poor vitamin K1 status.

Clinical Reference

1. Office of Dietary Supplements: Vitamin K Fact Sheet for Health Professionals. National Institutes of Health; Updated March 29, 2021. Accessed April 23, 2024. Available at https://ods.od.nih.gov/factsheets/vitaminK-HealthProfessional/

2. Lippi G, Franchini M. Vitamin K in neonates: Facts and myths. Blood Transfus. 2011;9(1):4-9. doi:10.2450/2010.0034-10

3. Greer FR. Vitamin K the basics-What's new? Early Hum Dev. 2010;86 Suppl 1:43-7. doi:10.1016/j.earlhumdev.2010.01.015

Day(s) Performed

Monday through Friday

Report Available

2 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

84597

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VITK1 Vitamin K1, S 9622-2

 

Result ID Test Result Name Result LOINC Value
62167 Vitamin K1, S 9622-2

Forms

If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.