Sign in →

Test Code VITE Vitamin E, Serum

Useful For

Monitoring of Vitamin E supplementation/treatment

 

Potentially detecting Vitamin E overdoses

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Vitamin E, S

Specimen Type

Serum


Shipping Instructions


Ship specimen in amber vial to protect from light.



Specimen Required


Patient Preparation: Patient should fast overnight (12-14 hours); infants should have specimen collected before next feeding.

Supplies: Amber Frosted Tube, 5 mL (T915)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Amber vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into light protected plastic vial within 2 hours of collection.


Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 44 days LIGHT PROTECTED
  Frozen  44 days LIGHT PROTECTED
  Ambient  7 days LIGHT PROTECTED

Reference Values

0-17 years: 3.8-18.4 mg/L

≥18 years: 5.5-17.0 mg/L

Interpretation

Vitamin E concentrations within the healthy reference population range usually indicate adequate Vitamin A stores.

 

The rare occurrence of low Vitamin A levels might correlate with potential deficiency and investigation of potential fat malabsorptions should be considered.

 

Conversely, Vitamin E concentrations significantly above the upper healthy reference population range might indicate that Vitamin E intake exceeds the tolerable upper daily intake level(s).

Clinical Reference

1. Ball GFM. Vitamins: Their role in the human body. Oxford, Blackwell Publishing. 2004:234-255

2. Traber MG. Vitamin E. In: Shils ME, Shike M, Ross AC, et al, eds. Modern Nutrition in Health and Disease.10th ed. Lippincott Williams and Wilkins; 2006:434-441

3. Roberts NB, Taylor A, Sodi R. Vitamins and trace elements. In: Rifai N, Horvath AR, Wittwer CT, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6th ed. Elsevier; 2018:chap37

4. Sodi R. Vitamins and trace elements. In: Rifai N, Chiu RWK, Young I, Burnham C-AD, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. Elsevier; 2023:417-417.e104

Day(s) Performed

Sunday through Friday

Report Available

3 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

84446

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VITE Vitamin E, S 1823-4

 

Result ID Test Result Name Result LOINC Value
2350 A-Tocopherol, Vitamin E 1823-4

Forms

If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.