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HelpTest Code UNHB Hemoglobin Stability, Blood
Reporting Name
Hb Stability, BUseful For
Work-up of congenital hemolytic anemias
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
Whole Blood EDTASpecimen Required
Only orderable as part of a profile or as a reflex. For more information see:
-HAEV1 / Hemolytic Anemia Evaluation, Blood
-HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood
-THEV1 / Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum
-REVE2 / Erythrocytosis Evaluation, Blood
-MEV1 / Methemoglobinemia Evaluation, Blood
Container/Tube: Lavender top (EDTA)
Specimen Volume: 4 mL
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole Blood EDTA | Refrigerated | 7 days |
Reference Values
Only orderable as part of a profile or as a reflex. For more information see:
-HAEV1 / Hemolytic Anemia Evaluation, Blood
-HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood
-THEV1 / Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum
-REVE2 / Erythrocytosis Evaluation, Blood
-MEV1 / Methemoglobinemia Evaluation, Blood
Normal (reported as normal [stable] or abnormal [unstable])
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
83068
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| UNHB | Hb Stability, B | 4639-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 9095 | Hb Stability, B | 4639-1 |
Interpretation
An abnormal or unstable result is indicative of a hemoglobin variant present. Other confirmatory tests should be performed to identify the hemoglobinopathy (HBEL1 / Hemoglobin Electrophoresis Cascade, Blood).
Clinical Reference
1. Hoyer JD, Hoffman DR. The thalassemia and hemoglobinopathy syndromes. In: McClatchey KD, Amin HM, Curry JL, eds. Clinical Laboratory Medicine. 2nd ed. Lippincott Williams and Wilkins; 2002:866-895
2. Benz EJ, Ebert BL. Hemoglobin variants associated with hemolytic anemia, altered oxygen affinity, and methemoglobinemias. In: Hoffman R, Benz EJ, Silberstein LE, et al. eds. Hematology: Basic Principles and Practice. 7th ed. Elsevier; 2018:608-615
Method Name
Only orderable as part of a profile or as a reflex. For more information see:
-HAEV1 / Hemolytic Anemia Evaluation, Blood
-HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood
-THEV1 / Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum
-REVE2 / Erythrocytosis Evaluation, Blood
-MEV1 / Methemoglobinemia Evaluation, Blood
Isopropanol and Heat Stability
Day(s) Performed
Monday through Friday