Sign in →

Test Code TOXB Toxoplasma gondii, Molecular Detection, PCR, Blood

Useful For

Supporting the diagnosis of active toxoplasmosis, particularly in immunocompromised individuals

Reporting Name

Toxoplasma gondii PCR, B

Specimen Type

Whole Blood EDTA


Specimen Required


Container/Tube: Lavender top (EDTA)

Specimen Volume: 1 mL

Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole Blood EDTA Refrigerated (preferred) 7 days
  Frozen  7 days

Reference Values

Negative

Interpretation

A positive result indicates presence of DNA from Toxoplasma gondii.

 

Negative results indicate absence of detectable DNA, but do not exclude the presence of organism or active or recent disease.

Clinical Reference

1. Robert-Gangneux F, Darde M. Epidemiology of and diagnostic strategies for toxoplasmosis. Clin Microbiol Rev. 2012 Apr ;25(2):264-296

2. McAuley JB, Singh K: Toxoplasma, In: Carroll KC, Pfaller MA, eds. Manual of Clinical Microbiology, 12th ed. ASM Press; 2019: chap141.

3. Mattos CCB, Meira CS, Ferreira AIC, et al: Contribution of laboratory methods in diagnosing clinically suspected ocular toxoplasmosis in Brazilian patients. Diagn Microbiol Infec Dis. 2011 Jul;70(3):362-366

4. Martino R, Bretagne S, Einsele H, et al: Early detection of Toxoplasma infection by molecular monitoring of Toxoplasma gondii in peripheral blood samples after allogeneic stem cell transplantation. Clin Infect Dis. 2005 Jan 1;40(1):67-78

5. Fricker-Hidalgo H, Bulabois C, Brenier-Pinchart M, et al: Diagnosis of toxoplasmosis after allogeneic stem cell transplantation: results of DNA detection and serological techniques. Clin Infect Dis. 2009;48:e9-e15

Day(s) Performed

Monday through Saturday

Report Available

Same day/1 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

87798

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TOXB Toxoplasma gondii PCR, B 16279-2

 

Result ID Test Result Name Result LOINC Value
62977 Toxoplasma gondii PCR, B 16279-2

Method Name

Polymerase Chain Reaction (PCR)/DNA Probe Hybridization

Forms

If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.