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HelpTest Code SULFU Sulfate, 24 Hour, Urine
Reporting Name
Sulfate, 24 Hr, UUseful For
Assessing the nutrition intake of animal protein
The calculation of urinary supersaturation of various crystals or stones
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
UrineNecessary Information
24-Hour volume (in milliliters) is required.
Specimen Required
Supplies: Sarstedt 5 mL Aliquot Tube (T914)
Container/Tube: Plastic, 5-mL urine tube
Specimen Volume: 4 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. Collection instructions with no preservative:
-Specimen must be kept refrigerated during and after collection.
3. Collection instructions with preservative:
 a. If preservative is not added before collection, the specimen must be kept refrigerated until preservative is added.
 b. Preservative must be added within 4 hours of the end of collection.
4. Specimen pH should be between 4.5 and 8 and will stay in this range if kept refrigerated. Specimens with pH >8 indicate bacterial contamination, and testing will be cancelled. Do not attempt to adjust pH as it will adversely affect results.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days |
Special Instructions
Reference Values
7-47 mmol/24 hours
Day(s) Performed
Monday through Friday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
84392
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| SULFU | Sulfate, 24 Hr, U | 26889-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| SLF_U | Sulfate, 24 Hr, U | 26889-6 |
| TM89 | Collection Duration | 13362-9 |
| VL71 | Urine Volume | 3167-4 |
| SUL_C | Sulfate Concentration, 24 Hr, U | 12920-5 |
Interpretation
Urinary sulfate is a reflection of dietary protein intake, particularly of meat, and thus can be used as an index of nutritional protein intake.
It also is used in the calculation of urinary supersaturation of various crystals or stones.
Clinical Reference
1. Rodgers A, Gauvin D, Edeh S, et al. Sulfate but not thiosulfate reduces calculated and measured urinary ionized calcium and supersaturation: implications for the treatment of calcium renal stones. PLoS ONE. 2014;9(7):e103602. doi:10.1371/journal.pone.0103602
2. Magee EA, Curno R, Edmond LM, Cummings JH. Contribution of dietary protein and inorganic sulfur to urinary sulfate: toward a biomarker of inorganic sulfur intake. Am J Clin Nutr. 2004;80(1):137-142
3. Houterman S, van Faassen A, Ocke MC, et al. Is urinary sulfate a biomarker for the intake of animal protein and meat?. Cancer Lett. 1997;114(1-2):295-296
Report Available
1 to 3 daysMethod Name
High-Pressure Ion Chromatography (HPIC)
Forms
If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.