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Test Code STRNG Strongyloides Antibody, IgG, Serum

Useful For

Screening for the presence of IgG-class antibodies to Strongyloides

 

This test is not useful for monitoring patient response to therapy as IgG-class antibodies to Strongyloides may remain detectable following resolution of infection.

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

Strongyloides Ab, IgG, S

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 30 days
  Frozen  30 days

Reference Values

Negative

Reference values apply to all ages.

Interpretation

Positive:

IgG antibodies to Strongyloides were detected, suggesting current or past infection. False-positive results may occur with other helminth infections (eg, Trichinella, Taenia solium). Clinical correlation is required.

 

Negative:

No detectable levels of IgG antibodies to Strongyloides. Repeat testing in 10 to 14 days if clinically indicated.

Clinical Reference

1. Ramanathan R, Burbelo PD, Groot S, et al: A luciferase immunoprecipitation systems assay enhances the sensitivity and specificity of diagnosis of Strongyloides stercoralis infection. J Infect Dis. 2008;198(3):444-451

2. Starr MC, Montgomery SP: Soil-transmitted Helminthiasis in the United States: a systematic review-1940-2010. Am J Trop Med Hyg. 2011;85(4):680-684

3. Krolewiecki AJ, Ramanathan R, Fink V, et al: Improved diagnosis of Strongyloides stercoralis using recombinant antigen-based serologies in a community-wide study in northern Argentina. Clin Vaccine Immunol. 2010;17(10):1624-1630

4. Centers for Disease Control and Prevention. Global Health. Division of Parasitic Diseases and Malaria: Parasites-Strongyloides: Epidemiology and Risk Factors. CDC; Updated December 31, 2018. Accessed October 15, 2020. Available at www.cdc.gov/parasites/strongyloides/epi.html

Day(s) Performed

Monday, Wednesday, Thursday, Friday

Report Available

Same day/1 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86682

LOINC Code Information

Test ID Test Order Name Order LOINC Value
STRNG Strongyloides Ab, IgG, S 34376-4

 

Result ID Test Result Name Result LOINC Value
STRNG Strongyloides Ab, IgG, S 80660-4

Testing Algorithm

For more information see Parasitic Investigation of Stool Specimens Algorithm.

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.