Test Code SAT Percent Saturation
Specimen Required
Only orderable as part of profile. For more information see SFEC / Iron and Total Iron-Binding Capacity, Serum
Useful For
Calculation of percent saturation
Method Name
Only orderable as part of profile. For more information see SFEC / Iron and Total Iron-Binding Capacity, Serum
Calculation
Reporting Name
Percent SaturationSpecimen Type
SerumSpecimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 21 days | |
Frozen | 365 days |
Reference Values
Only orderable as part of profile. For more information see SFEC / Iron and Total Iron-Binding Capacity, Serum
14-50%
Interpretation
Percent saturation often exceeds 45% in hereditary hemochromatosis and 90% in advanced iron overload states.(2)
Percent saturation less than 16% is generally used to screen for iron deficiency, but a threshold of 20% is used in the presence of inflammation.(3)
Clinical Reference
1. Swinkels DW. Iron metabolism. In: Rifai N, Chiu RWK, Young I, Burnham CAD, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. Elsevier. 2023:chap 40
2. Kowdley KV, Brown KE, Ahn J, Sundaram V. ACG Clinical Guideline: Hereditary Hemochromatosis [published correction appears in Am J Gastroenterol. 2019 Dec;114(12):1927. doi:10.14309/ajg.0000000000000469]. Am J Gastroenterol. 2019;114(8):1202-1218. doi:10.14309/ajg.0000000000000315
3. Lopez A, Cacoub P, Macdougall IC, Peyrin-Biroulet L. Iron deficiency anaemia. Lancet. 2016;387(10021):907-916. doi:10.1016/S0140-6736(15)60865-0
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 to 2 daysPerforming Laboratory
Mayo Clinic Laboratories in RochesterTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.LOINC Code Information
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
SAT | Percent Saturation | 2502-3 |