Test Code SASP Aspergillus fumigatus, IgG Antibodies, Serum
Reporting Name
Aspergillus fumigatus, IgG Ab, SUseful For
Evaluation of patients suspected of having hypersensitivity pneumonitis (HP) induced by exposure to Aspergillus fumigatus
Evaluation of patients suspected of having HP who have documented environmental exposures to high-humidity environments
Performing Laboratory
Mayo Clinic Laboratories in RochesterSpecimen Type
SerumSpecimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 21 days | |
Frozen | 21 days |
Reference Values
<4 years: not established
≥4 years: ≤102 mg/L
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86606
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
SASP | Aspergillus fumigatus, IgG Ab, S | 26954-8 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
SASP | Aspergillus fumigatus, IgG Ab, S | 26954-8 |
Interpretation
Positive results for IgG antibodies to Aspergillus fumigatus, in patients with signs and symptoms of hypersensitivity pneumonitis, may be consistent with sensitization to this fungus.
Clinical Reference
1. Sforza GG, Marinou A: Hypersensitivity pneumonitis: a complex lung disease. Clin Mol Allergy. 2017; Mar 7;15(6). doi: 10.1186/s12948-017-0062-7
2. Costabel U, Miyazaki Y, Pardo A, et al: Hypersensitivity pneumonitis. Nat Rev Dis Primers. 2020 Aug 6;6(1):65. doi: 10.1038/s41572-020-0191-z
3. Raghu G, Remy-Jardin M, Ryerson CJ, et al: Diagnosis of hypersensitivity pneumonitis in adults. An Official ATS/JRS/ALAT Clinical Practice Guideline. Am J Respir Crit Care Med. 2020 August 1;202(3):e36-e69. doi: 10.1164/rccm.202005-2032ST
Report Available
2 to 4 daysMethod Name
Fluorescence Enzyme Immunoassay (FEIA)
Day(s) Performed
Monday through Friday