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Test Code RPR2 Respiratory Profile, Region 2, Mid-Atlantic (DC, DE, MD, NC, VA), Serum

Important Note

This panel includes IgE, do not order it in addition to the panel.

Useful For

Assessing sensitization to various inhalant allergens commonly found in the Mid-Atlantic region including the District of Columbia, Delaware, Maryland, North Carolina, and Virginia

 

Defining the allergen responsible for eliciting signs and symptoms

 

Identifying allergens:

-Responsible for allergic response and/or anaphylactic episode

-To confirm sensitization prior to beginning immunotherapy

-To investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens

Profile Information

Test ID Reporting Name Available Separately Always Performed
IGE Immunoglobulin E (IgE), S Yes Yes
DP House Dust Mites/D.P., IgE Yes Yes
DF House Dust Mites/D.F., IgE Yes Yes
CAT Cat Epithelium, IgE Yes Yes
DOGD Dog Dander, IgE Yes Yes
BERG Bermuda Grass, IgE Yes Yes
TIMG Timothy Grass, IgE Yes Yes
JOHN Johnson Grass, IgE Yes Yes
COCR Cockroach, IgE Yes Yes
PENL Penicillium, IgE Yes Yes
CLAD Cladosporium, IgE Yes Yes
ASP Aspergillus Fumigatus, IgE Yes Yes
ALTN Alternaria Tenuis, IgE Yes Yes
BXMPL Box Eld/Maple, S, IgE Yes Yes
BIR Silver Birch, IgE Yes Yes
CED Mountain Cedar, IgE Yes Yes
OAK Oak, IgE Yes Yes
ELM Elm, IgE Yes Yes
CTWD Cottonwood, IgE Yes Yes
PCANH Pecan Hickory, IgE Yes Yes
MULB Mulberry, IgE Yes Yes
SRW Short Ragweed, IgE Yes Yes
RRRP Rough Pigweed, IgE Yes Yes
SORR Red Sorrel, IgE Yes Yes

Reporting Name

Resp Profile, Reg 2, Mid-Atlantic

Specimen Type

Serum


Ordering Guidance


For a listing of allergens available for testing, see Allergens - Immunoglobulin E (IgE) Antibodies.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1.7 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

1.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  90 days

Reference Values

Specific IgE:

Class

IgE kU/L

Interpretation

0 

<0.10 

Negative 

0/1 

0.10-0.34 

Borderline/equivocal 

1 

0.35-0.69 

Equivocal 

2 

0.70-3.49 

Positive 

3 

3.50-17.4 

Positive 

4 

17.5-49.9 

Strongly positive 

5 

50.0-99.9 

Strongly positive 

6 

≥100 

Strongly positive 

 

Reference values apply to all ages.

 

Total IgE:

Age

Reference interval (in kU/L)

0-5 months

≤13

6-11 months

≤34

1 and 2 years

≤97

3 years

≤199

4-6 years

≤307

7 and 8 years

≤403

9-12 years

≤696

13-15 years

≤629

16 and 17 years

≤537

18 years and older

≤214

Interpretation

Elevated concentrations of total IgE may be found in a variety of clinical diseases, including allergic disease, certain primary immunodeficiencies, infections, inflammatory diseases, and malignancies.

 

Detection of allergen-specific IgE antibodies in serum (class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.

Clinical Reference

1. Homburger HA, Hamilton RG: Chapter 55: Allergic diseases. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 23rd ed. Elsevier; 2017:1057-1070

2. Bernstein IL, Li JT, Bernstein DI, et al: Allergy diagnostic testing: An updated practice parameter. Ann Allergy Asthma Immunol. 2008 Mar;100(3 Suppl 3):S1-148

Day(s) Performed

Monday through Friday

Report Available

Same day/1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

82785-IgE

86003 x 23-Each individual allergen

LOINC Code Information

Test ID Test Order Name Order LOINC Value
RPR2 Resp Profile, Reg 2, Mid-Atlantic 48825-4

 

Result ID Test Result Name Result LOINC Value
ALTN Alternaria Tenuis, IgE 6020-2
ASP Aspergillus Fumigatus, IgE 6025-1
BERG Bermuda Grass, IgE 6041-8
BIR Silver Birch, IgE 15283-5
BXMPL Box Eld/Maple, S, IgE 7155-5
CAT Cat Epithelium, IgE 6833-8
CED Mountain Cedar, IgE 6178-8
CLAD Cladosporium, IgE 53760-5
COCR Cockroach, IgE 6078-0
CTWD Cottonwood, IgE 6090-5
DF House Dust Mites/D.F., IgE 6095-4
DOGD Dog Dander, IgE 6098-8
DP House Dust Mites/D.P., IgE 6096-2
ELM Elm, IgE 6109-3
IGE Immunoglobulin E (IgE), S 19113-0
JOHN Johnson Grass, IgE 6152-3
MULB Mulberry, IgE 6281-0
OAK Oak, IgE 6189-5
PENL Penicillium, IgE 6212-5
RRRP Rough Pigweed, IgE 6233-1
SORR Red Sorrel, IgE 6244-8
SRW Short Ragweed, IgE 6085-5
TIMG Timothy Grass, IgE 6265-3
PCANH Pecan Hickory, IgE 6208-3

Method Name

Fluorescence Enzyme Immunoassay (FEIA)

Forms

If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen.

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.