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Test Code QUIN Quinidine, Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Red top (serum gel/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.


Useful For

Assessing and adjusting quinidine dosage for optimal therapeutic level

 

Assessing quinidine toxicity

Method Name

Kinetic Interaction of Microparticles in Solution (KIMS)

Reporting Name

Quinidine, S

Specimen Type

Serum Red

Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 14 days
  Frozen  28 days
  Ambient  14 days

Reference Values

Therapeutic: 2.0-5.0 mcg/mL

Critical value: ≥6.0 mcg/mL

Interpretation

Optimal response to quinidine occurs when the serum level is between 2.0 to 5.0 mcg/mL.

Clinical Reference

1. Milone MC, Shaw LM. Therapeutic drugs and their management. In: Rifai N, Chiu RWK, Young I, Burnham C-AD, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. Elsevier; 2023:420-453.e9.

2. Brunton LL, Hilal-Dandan R, Knollmann BC, eds. Goodman and Gilman's: The Pharmacological Basis of Therapeutics. McGraw-Hill; 2018

Day(s) Performed

Monday through Saturday

Report Available

Same day/1 to 2 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80194

LOINC Code Information

Test ID Test Order Name Order LOINC Value
QUIN Quinidine, S 6694-4

 

Result ID Test Result Name Result LOINC Value
8302 Quinidine, S 6694-4

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.