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Test Code QFEVR Q Fever Antibody Screen with Titer Reflex, Serum


Ordering Guidance


 



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.6 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Useful For

Screening for exposure to Coxiella burnetii, the causative agent of Q fever

 

This test should not be used as a screening procedure for the general population.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
QFP Q Fever IgM/IgG, Titer, S No No

Testing Algorithm

If the Q fever serology result is reactive, then Q fever antibody confirmation by indirect immunofluorescence will be performed at an additional charge.

 

For more information see Infective Endocarditis: Diagnostic Testing for Identification of Microbiological Etiology.

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

Q Fever Ab Scrn w/ Titer Reflex, S

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  7 days

Reference Values

Negative

Reference values apply to all ages

Interpretation

Negative:

No antibodies to Q fever (Coxiella burnetii) detected. Repeat testing on a new sample collected in 2 to 3 weeks if acute Q fever is suspected.

 

Reactive:

Not diagnostic. Sample reflexed to the indirect immunofluorescence assay to determine Q fever (Coxiella burnetii) phase I and phase II IgM and IgG titers.

Clinical Reference

1. Hartzell JD, Marrie TJ, Raoult D. Coxiella burnetii (Q fever). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Elsevier; 2020:2360-2367

2. Anderson A, Bijlmer H, Fournier PE, et al. Diagnosis and management of Q fever--United States, 2013: recommendations from CDC and the Q Fever Working Group [published correction appears in MMWR Recomm Rep. 2013 Sep 6;62(35):730]. MMWR Recomm Rep. 2013;62(RR-03):1-30

Day(s) Performed

Sunday through Friday

Report Available

1 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86638

86638 x 4 (if applicable)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
QFEVR Q Fever Ab Scrn w/ Titer Reflex, S 23019-3

 

Result ID Test Result Name Result LOINC Value
QFEVR Q Fever Ab Scrn w/ Titer Reflex, S 23019-3

Forms

If not ordering electronically, complete, print, and send an Infectious Disease Serology Test Request (T916) with the specimen.