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Test Code PARVO Parvovirus B19, Molecular Detection, PCR, Varies

Reporting Name

Parvovirus B19 PCR

Useful For

Diagnosing parvovirus B19 infection

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Varies


Necessary Information


Specimen source is required.



Specimen Required


Submit only 1 of the following specimens:

 

Preferred:

Specimen Type: Amniotic fluid

Container/Tube: Amniotic fluid container

Specimen Volume: 0.5 mL

Collection Instructions:

1. Do not centrifuge.

2. Label specimen as amniotic fluid.

 

Specimen Type: Spinal fluid

Container/Tube: Sterile vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Do not centrifuge.

2. Label specimen as spinal fluid.

 

Specimen Type: Synovial fluid

Container/Tube: Sterile vial or lavender top (EDTA)

Specimen Volume: 0.5 mL

Collection Instructions: Label specimen as synovial fluid.

 

Alternate:

Specimen Type: Bone marrow

Container/Tube: Sterile container or lavender top (EDTA)

Specimen Volume: 0.5 mL

Collection Instructions: Label specimen as bone marrow.


Specimen Minimum Volume

Amniotic Fluid, Bone Marrow, and Spinal Fluid 0.3 mL; Synovial fluid 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Refrigerated (preferred) 7 days
  Frozen  7 days

Reference Values

Negative

Day(s) Performed

Monday through Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

87798

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PARVO Parvovirus B19 PCR 9571-1

 

Result ID Test Result Name Result LOINC Value
SRC73 Source 31208-2
83151 Parvovirus B19 By Rapid PCR 9571-1

Interpretation

A positive result indicates that parvovirus B19 DNA is present in the clinical sample. However, a positive result does not differentiate between actively replicating virus, transient infection that may be asymptomatic, or the presence of remnant viral nucleic acid.

 

A negative result suggests the absence of parvovirus B19 infection.

Clinical Reference

1. Guo J, Wang Y, Zhang M, et al: Human parvovirus B19 infection in hospitalized patients suspected of infection with pathogenic microorganism. Front Cell Infect Microbiol. 2022 Dec 21;12:1083839

2. Heegaard ED, Brown KE: Human parvovirus B19. Clin Microbiol Rev 2002 Jul;15(3):485-505

3. Bultmann BD, Klingel K, Soltar K, et al: Fatal parvovirus B19 associated myocarditis clinically mimicking ischemic heart disease: an endothelial cell-mediated disease. Hum Pathol. 2003 Jan;34(1):92-95

4. Rerolle JP, Helal I, Morelon E: Parvovirus B19 infection after renal transplantation. Nephrologie. 2003;24(6):309-315

5. Chisaka H, Morita E, Yaegashi N: Parvovirus B19 and the pathogenesis of anaemia. Rev Med Virol. 2003 Nov-Dec; 13(6):347-359

Report Available

Same day/1 to 3 days

Method Name

Real-Time Polymerase Chain Reaction (PCR)/DNA Probe Hybridization

Forms

If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.