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HelpTest Code MSFNG Fibronectin Glomerulopathy Confirmation, Mass Spectrometry
Necessary Information
Preliminary pathology report, history, and electron microscopy images are required.
Specimen Required
Supplies: Pathology Packaging Kit (T554)
Specimen Type: Formalin-fixed, paraffin-embedded kidney tissue block
Collection Instructions: Do not send fixed tissue slides. Testing can only be done on paraffin-embedded tissue blocks.
Useful For
Aiding in the diagnosis of fibronectin glomerulopathy
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| MLCPC | Microdissection, Laser Capture | No, (Bill Only) | No |
| MSPTC | Mass Spectrometry | No, (Bill Only) | No |
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
FNG Confirm, LC MSSpecimen Type
SpecialSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Special | Ambient (preferred) | |
| Frozen | ||
| Refrigerated | ||
Interpretation
An interpretation will be provided.
Clinical Reference
1. Lusco MA, Chen Y, Cheng H, et al. AJKD atlas of renal pathology: Fibronectin glomerulopathy. Am J Kidney Dis. 2017;70(5):e21-e22. doi:10.1053/j.ajkd.2017.09.001
2. Ishimoto I, Sohara E, Ito E, Okado T, Rai T, Uchida S. Fibronectin glomerulopathy. Clin Kidney J. 2013;6(5):513-515. doi:10.1093/ckj/sft097
3. Satoskar AA, Shapiro JP, Bott CN, et al. Characterization of glomerular diseases using proteomic analysis of laser capture microdissected glomeruli. Mod Path. 2012;25(5):709-721. doi:10.1038/modpathol.2011.205
4. Castelletti F, Donadelli R, Banterla F, et al. Mutations in FN1 cause glomerulopathy with fibronectin deposits. Proc Natl Acad Sci U S A. 2008;105(7):2538-2543. doi:10.1073/pnas.0707730105
Day(s) Performed
Monday through Friday
Report Available
7 to 15 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82542
88380
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MSFNG | FNG Confirm, LC MS | 65757-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 615306 | Interpretation | 50595-8 |
| 615307 | Participated in the Interpretation | No LOINC Needed |
| 615308 | Report electronically signed by | 19139-5 |
| 615309 | Material Received | 81178-6 |
| 615310 | Disclaimer | 62364-5 |
| 615311 | Case Number | 80398-1 |
| 617017 | Gross Description | 22634-0 |
| 617018 | Addendum | 35265-8 |
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-Kidney Transplant Test Request
-Renal Diagnostics Test Request (T830)