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HelpTest Code MEVI Methemoglobinemia Interpretation
Useful For
Interpretation of the methemoglobinemia evaluation results
Diagnosis of methemoglobinemia and sulfhemoglobinemia and possible hereditary (congenital) causes
Differentiation of methemoglobinemia and sulfhemoglobinemia from other causes of cyanosis (eg, congenital heart disease)
Method Name
Only orderable as part of a profile. For more information see MEV1 / Methemoglobinemia Evaluation.
Medical Interpretation
Reporting Name
Methemoglobinemia InterpretationSpecimen Type
Whole Blood EDTASpecimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole Blood EDTA | Refrigerated | 72 hours |
Reference Values
Only orderable as part of a profile. For more information see MEV1 / Methemoglobinemia Evaluation.
Definitive results and an interpretive report will be provided.
Interpretation
This is a consultative evaluation in which the history and previous laboratory values are reviewed by a hematologist who is an expert on these disorders. Appropriate tests are performed and an interpretive report is issued.
Clinical Reference
1. OMIM: 250800 Methemoglobinemia due to deficiency of methemoglobin reductase. Updated May 20, 2019. Accessed January 22, 2024. Available at www.omim.org/entry/250800?search=250800&highlight=250800
2. OMIM: 250790 Methemoglobinemia and ambiguous genitalia. Updated December 9, 2022. Accessed January 22, 2024. Available at www.omim.org/entry/250790?search=250790&highlight=250790
3. OMIM: 141800 Hemoglobin alpha locus 1; HBA1. Updated September 15, 2023. Accessed January 22, 2024. Available at www.omim.org/entry/141800?search=141800&highlight=141800
4. OMIM: 141900 Hemoglobin beta locus; HBB. Updated September 15, 2023. Accessed January 22, 2024. Available at www.omim.org/entry/141900?search=141900&highlight=141900
5. Haymond S, Cariappa R, Eby CS, Scott MG. Laboratory assessment of oxygenation in methemoglobinemia. Clin Chem. 2005;51(2):434-444
6. Noor M, Beutler E. Acquired sulfhemoglobinemia. An underreported diagnosis?. West J Med. 1998;169(6):386-389
7. Thom CS, Dickson CF, Gell DA, Weiss MJ. Hemoglobin variants: biochemical properties and clinical correlates. Cold Spring Harb Perspect Med. 2013;3(3):a011858
8. Percy MJ, McFerran NV, Lappin TR. Disorders of oxidized haemoglobin. Blood Rev. 2005;19(2):61-68
9. Agarwal AM, Prchal JT. Methemoglobinemia and other dyshemoglobinemias. In: Kaushansky K, Lichtman MA, Prchal JT, et al. eds. Williams Hematology. 9th ed. McGraw-Hill Book Company; 2016:789-800
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
Not ApplicableCPT Code Information
83020-26
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MEVI | Methemoglobinemia Interpretation | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 608086 | Methemoglobinemia Interpretation | 59465-5 |
| 608108 | Reviewed By | 18771-6 |
Day(s) Performed
Monday through Friday