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HelpTest Code LPSC1 Lipid Panel, Serum
Specimen Required
Patient Preparation: Fasting is preferred but not required unless directed by the ordering provider.
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Serum gel tube must be centrifuged within 2 hours of collection.
2. Red-top tube must be centrifuged and the serum aliquoted into a plastic vial within 2 hours of collection.
Useful For
Managing atherosclerotic cardiovascular disease risk using serum specimens
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| CHOL | Cholesterol, Total, S | Yes | Yes |
| TRIG | Triglycerides, S | Yes, (Order TRIG1) | Yes |
| HDCH | Cholesterol, HDL, S | Yes | Yes |
| CLDL1 | Cholesterol, LDL, Calculated, S | No | Yes |
| NHDCH | Cholesterol, Non-HDL, Calculated, S | No | Yes |
| INTC1 | Fasting (8 HR or more) | No | Yes |
Method Name
CHOL, TRIG, HDCH: Enzymatic Colorimetric
CLDL1, NHDCH: Calculation
Reporting Name
Lipid Panel, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | |
| Frozen | 30 days |
Reference Values
The National Lipid Association and the National Cholesterol Education Program have set the following guidelines for lipids in a context of cardiovascular risk for adults 18 years and older:
TOTAL CHOLESTEROL
Desirable: <200 mg/dL
Borderline High: 200-239 mg/dL
High: ≥240 mg/dL
TRIGLYCERIDES
Normal: <150 mg/dL
Borderline High: 150-199 mg/dL
High: 200-499 mg/dL
Very High: ≥500 mg/dL
HIGH DENSITY LIPOPROTEIN (HDL) CHOLESTEROL
Males
≥40 mg/dL
Females
≥50 mg/dL
LOW DENSITY LIPOPROTEIN (LDL) CHOLESTEROL
Desirable: <100 mg/dL
Above Desirable: 100-129 mg/dL
Borderline High: 130-159 mg/dL
High: 160-189 mg/dL
Very High: ≥190 mg/dL
NON-HDL CHOLESTEROL
Desirable: <130 mg/dL
Above Desirable: 130-159 mg/dL
Borderline High: 160-189 mg/dL
High: 190-219 mg/dL
Very High: ≥220 mg/dL
The Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents has set the following guidelines for lipids in a context of cardiovascular risk for children ages 2-17:
Reference values have not been established for patients who are younger than 24 months.
TOTAL CHOLESTEROL
Acceptable: <170 mg/dL
Borderline High: 170-199 mg/dL
High: ≥200 mg/dL
TRIGLYCERIDES
2-9 years:
Acceptable: <75 mg/dL
Borderline High: 75-99 mg/dL
High: ≥100mg/dL
10-17 years:
Acceptable: <90 mg/dL
Borderline High: 90-129 mg/dL
High: ≥130 mg/dL
HDL CHOLESTEROL
Low HDL: <40 mg/dL
Borderline Low: 40-45 mg/dL
Acceptable: >45 mg/dL
LDL CHOLESTEROL
Acceptable: <110 mg/dL
Borderline High: 110-129 mg/dL
High: ≥130 mg/dL
NON-HDL CHOLESTEROL
Acceptable: <120 mg/dL
Borderline High: 120-144 mg/dL
High: ≥145 mg/dL
Interpretation
Maintaining desirable concentrations of lipids lowers atherosclerotic cardiovascular disease (ASCVD) risk. Establishing appropriate treatment strategies and lipid goals require blood lipid values be considered in context with other risk factors including, age, sex, smoking status, and medical history of hypertension, diabetes, and cardiovascular disease.
Triglycerides results of 500 mg/dL or above are severely elevated increasing the risk of pancreatitis. Triglycerides can be lowered by increasing physical activity, low-fat diet, weight loss, and/or triglyceride lowering pharmaceuticals.
Low high-density lipoprotein cholesterol is a risk factor for cardiovascular disease.
High density lipoprotein (HDL) cholesterol can be increased by the same lifestyle changes that reduce risk for cardiovascular disease; physical activity, smoking cessation, and eating healthier. However, medications that specifically increase HDL levels have failed to reduce cardiovascular disease. Extremely low HDL values (<20 mg/dL) may indicate liver disease or inherited dyslipidemia.
Low-density lipoprotein cholesterol results of 190 mg/dL or above in adults (≥160 mg/dL in children) are severely elevated and may indicate familial hypercholesterolemia.
For non-HDL cholesterol results of 220 mg/dL or above, a possible inherited hyperlipidemia diagnosis should be considered.
Clinical Reference
1. Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019;139(25):e1082-e1143
2. Jacobson TA, Ito MK, Maki KC, et al. National Lipid Association recommendations for patient-centered management of dyslipidemia: Part 1-executive summary. J Clin Lipidol. 2014;8(5):473-488. doi:10.1016/j.jacl.2014.07.007
3. Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents; National Heart, Lung, and Blood Institute. Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: Summary report. Pediatrics. 2011;128 Suppl 5(Suppl 5):S213-S256. doi:10.1542/peds.2009-2107C
4. Sampson M, Ling C, Sun Q, et al. A new equation for calculation of low-density lipoprotein cholesterol in patients with normolipidemia and/or hypertriglyceridemia. JAMA Cardiol. 2020;5(5):540-548
Day(s) Performed
Monday through Sunday
Report Available
1 dayPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
80061-Lipid panel (if all 3 performed)
82465-Cholesterol, total (if all 3 are not performed)
84478-Triglycerides (if all 3 are not performed)
83718-Cholesterol, HDL (if all 3 are not performed)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| LPSC1 | Lipid Panel, S | 24331-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| CHOL | Cholesterol, Total, S | 2093-3 |
| HDCH | Cholesterol, HDL, S | 2085-9 |
| NHDCH | Cholesterol, Non-HDL, Calculated, S | 43396-1 |
| TRIG | Triglycerides, S | 2571-8 |
| CLDL1 | Cholesterol, LDL, Calculated, S | 13457-7 |
| INTC1 | Fasting (8 HR or more) | 87527-8 |