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HelpTest Code HAEVI Hemolytic Anemia Interpretation
Useful For
Interpretation of the results for the evaluation of hemolytic anemia
Evaluation of lifelong or inherited hemolytic anemias, including red blood cell membrane disorders, unstable or abnormal hemoglobin variants, and red blood cell enzyme disorders
This evaluation is not suitable for acquired causes of hemolysis.
Method Name
Only orderable as part of a profile. For more information see HAEV1 / Hemolytic Anemia Evaluation, Blood.
Medical Interpretation
Reporting Name
Hemolytic Anemia InterpretationSpecimen Type
Whole Blood ACD-BSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole Blood ACD-B | Refrigerated | 72 hours |
Reference Values
Only orderable as part of a profile. For more information see HAEV1 / Hemolytic Anemia Evaluation, Blood.
Definitive results and an interpretive report will be provided.
Interpretation
A hematopathologist expert in these disorders evaluates the case. A detailed interpretation is given, including an overview of the results and their significance, as well as clinical research information regarding different enzyme deficiencies.
Clinical Reference
1. Steiner LA, Gallagher PG. Erythrocyte disorders in the perinatal period. Semin Perinatol. 2007;31(4):254-261. doi:10.1053/j.semperi.2007.05.003
2. Beutler E. Glucose-6-phosphate dehydrogenase deficiency and other enzyme abnormalities. In: Beutler E, Lichtman MA, Coller BS, Kipps TJ, eds. Hematology. 5th ed. McGraw-Hill Book Company; 1995: 564-581
3. Hoyer JD, Hoffman DR. The thalassemia and hemoglobinopathy syndromes. In: McClatchey KD, Amin HM, Curry JL, eds. Clinical Laboratory Medicine. 2nd ed. Lippincott, Williams and Wilkins; 2002: 866-895
4. King MJ, Garcon L, Hoyer JD, et al. International Council for Standardization in Haematology. ICSH guidelines for the laboratory diagnosis of nonimmune hereditary red cell membrane disorders. Int J Lab Hematol. 2015;37(3):304-325. doi:10.1111/ijlh.12335
5. Lux SE. Anatomy of the red cell membrane skeleton: unanswered questions. Blood. 2016;127(2):187-199 doi:10.1182/blood-2014-12-512772
6. Gallagher PG. Abnormalities of the erythrocyte membrane. Pediatr Clin North Am. 2013;60(6):1349-1362. doi:10.1016/j.pcl.2013.09.001
7. Bianchi P, Fermo E, Vercellati C, et al. Diagnostic power of laboratory tests for hereditary spherocytosis: a comparison study in 150 patients grouped according to molecular and clinical characteristics. Haematologica. 2012;97(4):516-523. doi:10.3324/haematol.2011.052845
8. Cappellini MD, Fiorelli G. Glucose-6-phosphate dehydrogenase deficiency. Lancet. 2008;371(9606):64-74
9. Glader B. Hereditary hemolytic anemias due to red blood cell enzyme disorders. In: Greer JP, Arber DA, Glader B, et al, eds. Wintrobe's Clinical Hematology. 13th ed. Wolters Kluwer/Lippincott, Williams and Wilkins; 2014:728
10. Bartels M, Beers E, Wijk R. Erythrocyte enzyme disorders. In: Kaushansky K, Prchal JT, Burns LJ, Lichtman MA, Levi M, Linch DC. eds. Williams Hematology, 10th ed. McGraw-Hill Education; 2021:chap 48
11. Gallagher PG. Diagnosis and management of rare congenital nonimmune hemolytic disease. Hematology Am Soc Hematol Educ Program. 2015; 392-399. doi:10.1182/asheducation-2015.1.39211
12. Koralkova P, van Solinge WW, van Wijk R. Rare hereditary red blood cell enzymopathies associated with hemolytic anemia- pathophysiology, clinical aspects, and laboratory diagnosis. Int J Lab Hematol. 2014;36(3):388-397. doi:10.1111/ijlh.12223
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
Not ApplicableCPT Code Information
83020-26
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HAEVI | Hemolytic Anemia Interpretation | 59466-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 608427 | Hemolytic Anemia Interpretation | 59466-3 |
| 608441 | Reviewed By | 18771-6 |
Day(s) Performed
Monday through Friday