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Test Code FRUCT Fructosamine, Serum

Reporting Name

Fructosamine, S

Useful For

Monitoring intermediate (1-3 weeks) glycemic control

 

Monitoring glycemic control in patients with shortened red blood cell survival

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt 5 mL Aliquot Tube (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged and the serum aliquoted into a plastic vial within 2 hours of collection.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  60 days
  Ambient  72 hours

Reference Values

200-285 mcmol/L

Day(s) Performed

Monday through Sunday

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

82985

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FRUCT Fructosamine, S 15069-8

 

Result ID Test Result Name Result LOINC Value
FRUCT Fructosamine, S 15069-8

Interpretation

In general, fructosamine reflects glycemic control in diabetic patients over the previous 1 to 3 weeks. High values indicate poor control.

 

All glycated proteins are measured by this method, with glycated albumin contributing a large portion.

Clinical Reference

1. Sacks DB: Diabetes mellitus. In: Rifai N, Horvath AR, Wittwer CT, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6th ed. Elsevier; 2018:1194-1197

2. Masharani U, German MS: Pancreatic hormones and diabetes mellitus. In: Gardner DG, Shoback D, eds. Greenspan’s Basic and Clinical Endocrinology. 9th ed. McGraw; 2018:46-47

3. Austin GE, Mullins RH, Morin LG: Non-enzymatic glycation of individual plasma proteins in normoglycemic and hyperglycemic patients. Clin Chem. 1987;33:2220-2224

4. Schleicher ED, Mayer R, Wagner EM, Gerbitz KD: Is serum fructosamine assay specific for determination of glycated serum protein? Clin Chem. 1988;34:320-323

Report Available

Same day/1 to 2 days

Method Name

Colorimetric Rate Reaction