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HelpTest Code FIFLC Immunofixation with Free Light Chains, Quantitative, Urine
Specimen Required
Specimen Type: Urine
Submission Container/Tube: Two 4-mL plastic aliquot tube(s)
Specimen Volume: 8 mL (Two 4-mL plastic aliquot tube(s))
Collection Instructions:
1. Collect urine for 24 hours (NO preservative).
2. Refrigerate specimen during the 24-hour collection.
3. Send specimen refrigerate in Two 4-mL plastic aliquot tube(s)
4. Collection volume and duration are required
Method Name
Qualitative Immunofixation Electrophoresis/Quantitative Immunoturbidimetry
Reporting Name
Immunofix Free Light Chains, USpecimen Type
UrineSpecimen Minimum Volume
4 mL (2 vials 2 mL each)
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 21 days | |
| Frozen | 180 days |
Reference Values
|
Total Protein |
Less than 150 mg/d |
|
Free Urinary Kappa Light Chains |
0.00-32.90 mg/L |
|
Free Urinary Kappa Excretion/Day |
By report |
|
Free Urinary Lambda Light Chain |
0.00-3.79 mg/L |
|
Free Urinary Lambda Excretion/Day |
By report |
|
IFE Interpretation |
By report |
Interpretation
Results of urine free light chain testing can be used to monitor disease progression or response to therapy in patients for whom urine electrophoresis is unable to provide reliable Bence Jones Protein quantification. The results of urine kappa and lambda free light chain quantitative values may be misleading in specimens with high levels of urinary polyclonal free light chains, and absent Bence Jones protein by immunofixation; therefore correlation with urine immunofixation is required to identify inconsistent results. Total urinary protein is determined turbidmetrically by adding the albumin and kappa and/or lambda light chains. This value may not agree with the total protein as determined by chemical methods, which characteristically underestimates urinary light chains.
Performing Laboratory
ARUP LaboratoriesCPT Code Information
84156
86335
83521 x 2
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FIFLC | Immunofix Free Light Chains, U | Not Provided |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| Z5897 | Hours Collected | 30211-7 |
| Z5898 | Total Volume | 19153-6 |
| Z5899 | Total Protein | 2889-4 |
| Z5901 | Free Urinary Kappa Light Chains | 38176-4 |
| Z5912 | Free Urinary Kappa Excretion/Day | 38177-2 |
| Z5913 | Free Urinary Lambda Light Chain | 38178-0 |
| Z5914 | Free Urinary Lambda Excretion/Day | 38169-9 |
| Z5900 | IFE Interpretation | 49277-7 |
Day(s) Performed
Monday through Sunday