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Test Code ENTP Enterovirus, Molecular Detection, PCR, Plasma

Important Note

  • MUST be collected at the Outpatient Lab at the Hospital
  • Specimen must be spun down and plasma removed within 2 hours of collection

Reporting Name

Enterovirus PCR, P

Useful For

Aiding in diagnosing enterovirus infections using plasma specimens

 

This test should not be used to screen asymptomatic patients.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Plasma EDTA


Ordering Guidance


This test will detect enterovirus but will not differentiate viruses in this family or provide serotyping information.



Specimen Required


Submit a raw clinical sample (not a culture isolate) for enterovirus polymerase chain reaction .

 

Collection Container/Tube: Lavender top (EDTA)

Submission Container/Tube: Screw-capped, sterile container

Specimen Volume: 1 mL

Collection Instructions: Centrifuge blood collection tube and aliquot plasma into plastic vial.


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma EDTA Refrigerated (preferred) 7 days
  Frozen  7 days

Reference Values

Negative

Day(s) Performed

Monday through Sunday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

87498

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ENTP Enterovirus PCR, P 97151-5

 

Result ID Test Result Name Result LOINC Value
56068 Enterovirus PCR, P 97151-5

Interpretation

A positive result indicates the presence of enterovirus RNA in the specimen.

Clinical Reference

1. Harvala H, Broberg E, Benschop K, et al: Recommendations for enterovirus diagnostics and characterisation within and beyond Europe. J Clin Virol. 2018 Apr;101:11-17

2. Khetsuriani N, Lamonte-Fowlkes A, Oberst S, et al: Enterovirus surveillance-United States, 1970-2005. MMWR Surveill Summ, 2006 Sep 15;55(8):1-20

3. Foray S, Pailloud F, Thouvenot D, Floret D, Aymard M, Lina B: Evaluation of combining upper respiratory tract swab samples with cerebrospinal fluid examination for the diagnosis of enteroviral meningitis in children. J Med Virol. 1999 Feb;57(2):193-197

4. Furione M, Zavattoni M, Gatti M, Percivalle E, Fioroni N, Gerna G: Rapid detection of enteroviral RNA in cerebrospinal fluid (CSF) from patients with aseptic meningitis by reverse transcription-nested polymerase chain reaction. New Microbiol. 1998 Oct;21(4):343-351

Report Available

Same day/1 to 5 days

Method Name

Real-Time Polymerase Chain Reaction (PCR)/RNA Probe Hybridization

Forms

If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.