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HelpTest Code EHRCP Ehrlichia Antibody Panel, Serum
Reporting Name
Ehrlichia Ab PanelUseful For
An adjunct in the diagnosis of infection with Anaplasma phagocytophilum or Ehrlichia chaffeensis
Seroepidemiological surveys of the prevalence of the infection in certain populations
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| ANAP | Anaplasma phagocytophilum Ab, IgG,S | Yes | Yes |
| EHRC | Ehrlichia Chaffeensis (HME) Ab, IgG | Yes | Yes |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
See Specimen Required
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days |
Reference Values
ANAPLASMA PHAGOCYTOPHILUM
<1:64
Reference values apply to all ages.
EHRLICHIA CHAFFEENSIS
<1:64
Reference values apply to all ages.
Day(s) Performed
Monday through Friday
Test Classification
This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86666 x 2
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| EHRCP | Ehrlichia Ab Panel | 77165-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 81157 | Anaplasma phagocytophilum Ab, IgG,S | 23877-4 |
| 81478 | Ehrlichia Chaffeensis (HME) Ab, IgG | 47405-6 |
Testing Algorithm
For more information see Acute Tick-Borne Disease Testing Algorithm.
Special Instructions
Interpretation
A positive immunofluorescence assay result (titer ≥1:64) suggests current or previous infection. In general, the higher the titer, the more likely the patient has an active infection. Four-fold rises in titer also indicate active infection.
Previous episodes of ehrlichiosis may produce a positive serology result although antibody levels decline significantly during the year following infection.
Clinical Reference
Centers for Disease Control and Prevention (CDC), Division of Vector-Borne Diseases: Tickborne Diseases of the United States: A Reference Manual for Healthcare Providers. 6th ed. US Department of Health and Human Services; 2022. Accessed September 5, 2024. Available at www.cdc.gov/ticks/tickbornediseases/TickborneDiseases-P.pdf
Report Available
Same day/1 to 3 daysMethod Name
Immunofluorescence Assay (IFA)
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.