Test Code EHRC Ehrlichia chaffeensis (HME) Antibody, IgG, Serum
Reporting Name
Ehrlichia Chaffeensis (HME) Ab, IgGUseful For
An adjunct in the diagnosis of ehrlichiosis
Seroepidemiological surveys of the prevalence of the infection in certain populations
Performing Laboratory
Mayo Clinic Laboratories in RochesterSpecimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.4 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 14 days | |
Frozen | 14 days |
Reference Values
<1:64
Reference values apply to all ages.
Day(s) Performed
Monday through Friday
Test Classification
This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86666
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
EHRC | Ehrlichia Chaffeensis (HME) Ab, IgG | 47405-6 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
81478 | Ehrlichia Chaffeensis (HME) Ab, IgG | 47405-6 |
Interpretation
A positive immunofluorescence assay result (titer ≥1:64) suggests current or previous infection. In general, the higher the titer, the more likely the patient has an active infection. Four-fold rises in titer also indicate active infection.
Previous episodes of ehrlichiosis may produce a positive serology result although antibody levels decline significantly during the year following infection.
Clinical Reference
Centers for Disease Control and Prevention (CDC): Tickborne Diseases of the United States: A Reference Manual for Healthcare Providers. 6th ed. US Department of Health and Human Services; 2022. Accessed September 5, 2024. Available at www.cdc.gov/ticks/tickbornediseases/TickborneDiseases-P.pdf
Report Available
Same day/1 to 3 daysMethod Name
Immunofluorescence Assay (IFA)
Testing Algorithm
For more information see Acute Tick-Borne Disease Testing Algorithm
Special Instructions
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.