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Test Code DSS Drug Screen, Prescription/Over the Counter, Serum

Reporting Name

Drug Screen, Prescription/OTC, S

Useful For

Detection and identification of prescription or over the counter drugs frequently found in drug overdose or used with a suicidal intent

 

Qualitatively identifying drugs present in the specimen; quantification of identified drugs, when available, may be performed upon client request

 

This test is not intended for therapeutic drug monitoring or compliance testing.

 

This test is not intended for use in employment-related testing.

 

This test is not useful for drugs of abuse or illicit drug testing, including benzodiazepines, opioids, barbiturates, cocaine, amphetamine type stimulants.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum Red


Ordering Guidance


This test is not performed using chain of custody. For chain-of-custody testing, order DSSX / Drug Screen, Prescription/Over the Counter, Chain of Custody, Serum.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Red top (serum gel/SST tubes are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 2.75 mL

Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into plastic vial.


Specimen Minimum Volume

1.1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  3 hours

Reference Values

Drugs detected are presumptive. Additional testing may be required to confirm the presence of any drugs detected.

Day(s) Performed

Monday through Sunday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80307

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DSS Drug Screen, Prescription/OTC, S 20785-2

 

Result ID Test Result Name Result LOINC Value
31072 Drugs detected: 20785-2
31168 Chain of Custody 77202-0

Interpretation

The drugs that are detected by this test are listed in Prescription and Over-the-Counter Drug Screening List and Limits of Detection.

 

The pharmacology of each drug determines how the test should be interpreted. A detailed discussion of each drug is beyond the scope of this text. If a clinical interpretation is required, contact Mayo Clinic Laboratories at 800-533-1710 and ask to speak to a toxicology consultant.

 

Each report will indicate the drugs detected.

Clinical Reference

1. Langman LJ, Bechtel LK, Holstege CP. Clinical toxicology. In: Rifai N, Chiu RWK, Young I, Burnham CAD, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. Elsevier; 2023:chap 43

2. Baselt RC. Disposition of Toxic Drugs and Chemical in Man. 12th ed. Biomedical Publications; 2020

Report Available

3 days

Method Name

Gas Chromatography Mass Spectrometry (GC-MS)

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.