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HelpTest Code DLAU D-Lactate, Urine
Reporting Name
D-Lactate, UUseful For
Preferred test for diagnosing D-lactate acidosis, especially in patients with jejunoileal bypass and short-bowel syndrome
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
UrineSpecimen Required
Supplies: Urine Tubes, 10 mL (T068)
Container/Tube: Plastic urine tube
Specimen Volume: 0.50 mL
Collection Instructions:
1. Collect a timed or random urine specimen.
2. No preservative.
3. Immediately freeze specimen.
Specimen Minimum Volume
0.15 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Frozen (preferred) | 90 days | |
| Ambient | 90 days | ||
| Refrigerated | 90 days |
Reference Values
0.0-0.25 mmol/L
Day(s) Performed
Monday, Thursday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
83605
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| DLAU | D-Lactate, U | 14046-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8873 | D-Lactate, U | 14046-7 |
Interpretation
Increased levels are diagnostic.
Clinical Reference
1. Brandt RB, Siegel SA, Waters MG, Bloch MH. Spectrophotometric assay for D-(-)-lactate in plasma. Anal Biochem. 1980;102(1):39-46
2. Khrais A, Ali H, Choi S, Ahmed A, Ahlawat S. D-Lactic Acidosis in Short Bowel Syndrome. Cureus. 2022;14(5):e25471. doi:10.7759/cureus.25471
3. Bianchetti DGAM, Amelio GS, Lava SAG, et al. D-lactic acidosis in humans: systematic literature review. Pediatr Nephrol. 2018;33(4):673-681. doi:10.1007/s00467-017-3844-8
Report Available
3 to 6 daysMethod Name
Gas Chromatography Mass Spectrometry (GCMS) Stable Isotope Dilution Analysis