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Test Code DLAC D-Lactate, Plasma

Important Note

When a Lactic Acid requested do not order this test.

1. Lactic Acid is performed by Respiratory Therapy. They are ordered as a .POC Lactate, Venous

2. This test must be collected in OPL at the main hospital campus.

3. Phlebotomy staff will contact Respiratory Therapy staff for its collection.

Reporting Name

D-Lactate, P

Useful For

As an adjunct to urine D-lactate (preferred) for the diagnosis of D-lactate acidosis

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Plasma NaFl-KOx


Ordering Guidance


Urine is the preferred specimen for D-lactate determination, order DLAU / D-Lactate, Urine.

 

For determination of L-lactate (lactic acid), order LACS1 / Lactate, Plasma



Specimen Required


Supplies: Sodium Fluoride/Potassium Oxalate Tube, 2 mL (T275)

Collection Container/Tube:

Preferred: Sodium fluoride/potassium oxalate tube

Acceptable: Green top (sodium heparin)

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge, aliquot plasma into a plastic vial, and freeze immediately.

NOTE: If collecting in sodium heparin tubes, centrifugation must occur within one hour of collection.


Specimen Minimum Volume

0.15 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma NaFl-KOx Frozen (preferred) 91 days
  Ambient  91 days
  Refrigerated  91 days

Reference Values

0.0-0.25 mmol/L

Day(s) Performed

Monday, Thursday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83605

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DLAC D-Lactate, P 14045-9

 

Result ID Test Result Name Result LOINC Value
8878 D-Lactate, P 14045-9

Interpretation

Increased levels are consistent with D-lactic acidosis. However, because D-lactate is readily excreted, urine determinations are preferred.

Clinical Reference

1. Khrais A, Ali H, Choi S, Ahmed A, Ahlawat S. D-Lactic acidosis in short bowel syndrome. Cureus. 2022;14(5):e25471. doi:10.7759/cureus.25471

2. Bianchetti DGAM, Amelio GS, Lava SAG, et al. D-lactic acidosis in humans: systematic literature review. Pediatr Nephrol. 2018;33(4):673-681. doi:10.1007/s00467-017-3844-8

Report Available

3 to 6 days

Method Name

Gas Chromatography Mass Spectrometry (GCMS) Stable Isotope Dilution Analysis