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Test Code CRT2F Creatinine, 24 Hour, Urine


Specimen Required


Only orderable as part of a profile. For more information see:

-TLTE4 / Leukotriene E4, 24 Hour, Urine

-MCM24 / Mast Cell Mediators, 24 Hour, Urine


Useful For

Normalizing urinary analytes to account for the variation in urinary concentration

Method Name

Only orderable as part of a profile. For more information see:

-TLTE4 / Leukotriene E4, 24 Hour, Urine

-MCM24 / Mast Cell Mediators, 24 Hour, Urine

 

Enzymatic Colorimetric Assay

Reporting Name

Creatinine, 24 HR, U

Specimen Type

Urine

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Frozen (preferred) 30 days
  Refrigerated  30 days
  Ambient  14 days

Reference Values

Only orderable as part of a profile. For more information see:

-TLTE4 / Leukotriene E4, 24 Hour, Urine

-MCM24 / Mast Cell Mediators, 24 Hour, Urine

 

Normal values mg per 24 hours:

Males: 930-2955 mg/24 hours

Females: 603-1783 mg/24 hours

 

Reference values have not been established for patients who are younger than 18 years.

Interpretation

Decreased creatinine clearance indicates decreased glomerular filtration rate. This can be due to conditions, such as progressive kidney disease, or result from adverse effect on renal hemodynamics that are often reversible, including certain drugs or from decreases in effective renal perfusion (eg, volume depletion or heart failure).

 

Increased creatinine clearance is often referred to as "hyperfiltration" and is most frequently seen during pregnancy or in patients with diabetes mellitus before diabetic nephropathy has occurred. It may also occur with large dietary protein intake.

Clinical Reference

1. Delaney MP, Lamb EJ. Kidney disease. In: Rifai N, Horvath AR, Wittwer CT, eds: Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6th ed. Elsevier; 2018:1256-1323

2. Meeusen JW, Rule AD, Voskoboev N, Baumann NA, Lieske JC. Performance of cystatin C- and creatinine-based estimated glomerular filtration rate equations depends on patient characteristics. Clin Chem. 2015;61(10):1265-1272. doi:10.1373/clinchem.2015.243030

3. Newman DJ, Price CP. Renal function and nitrogen metabolites. In: Burtis CA, Ashwood ER, eds. Tietz Textbook of Clinical Chemistry. 3rd ed. WB Saunders Company; 1999:1204-1270

4. Kasiske BL, Keane WF. Laboratory assessment of renal disease: clearance, urinalysis, and renal biopsy. In: Brenner BM, ed. The Kidney. 6th ed. WB Saunders Company; 2000:1129-1170

Day(s) Performed

Monday through Sunday

Report Available

1 day

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CRT2F Creatinine, 24 HR, U 65634-8

 

Result ID Test Result Name Result LOINC Value
CR_AF Creatinine, 24 HR, U 2162-6
TM10F Collection Duration (h) 13362-9
VL8F Urine Volume (mL) 3167-4
CRF24 Creatinine Concentration, 24 HR, U 20624-3