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Test Code CHLM Chlamydia IgM, Immunofluorescence, Serum


Ordering Guidance


For suspected Chlamydia trachomatis infection, order either CTRNA / Chlamydia trachomatis, Nucleic Acid Amplification, Varies or CGRNA / Chlamydia trachomatis and Neisseria gonorrhoeae, Nucleic Acid Amplification, Varies.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.3 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Useful For

Assessing IgM antibody levels to aid in the clinical diagnosis of Chlamydia pneumoniae or Chlamydia psittaci infections

Testing Algorithm

This test includes testing for Chlamydia pneumoniae IgM, and Chlamydia psittaci IgM

Method Name

Micro-Immunofluorescent Antibody (MIF) Assay

Reporting Name

Chlamydia IgM, IFA, S

Specimen Type

Serum

Specimen Minimum Volume

0.15 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 30 days
  Frozen  30 days

Reference Values

Chlamydia pneumoniae

<1:10

 

Chlamydia psittaci

<1:10

Interpretation

Chlamydia pneumoniae, and Chlamydia psittaci

≥1:10

IgM endpoint titers of 1:10 or more are considered presumptive evidence of infection.

 

<1:10

IgM endpoint titers below 1:10 suggest that the patient does not have a current infection. These antibody levels may be found in patients with either no history of chlamydial infection or those with past infection whose antibody levels have dropped below detectable levels.

Clinical Reference

1. Schlossberg D. Psittacosis (due to Chlamydia psittaci). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Elsevier; 2020:2320-2322

2. Hammerschlag MR, Kohlhoff SA, Gaydos CA. Chlamydia pneumoniae. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Elsevier; 2020:2323-2331

Day(s) Performed

Monday, Thursday

Report Available

Same day/1 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86632 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CHLM Chlamydia IgM, IFA, S 10849-8

 

Result ID Test Result Name Result LOINC Value
619390 C. pneumoniae IgM In Process
619391 C. psittaci IgM In Process