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Test Code CDOMB Cadmium for Occupational Monitoring, Blood

Reporting Name

Cadmium Occupational Monitor, B

Useful For

Detecting exposure to cadmium, a toxic heavy metal, as a part of occupational monitoring

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Whole blood


Specimen Required


Patient Preparation: High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Supplies:

-Metal Free EDTA 3 mL Tube (T989)

-Metal Free B-D Tube (EDTA), 6 mL (T183)

Container/Tube:

Preferred: Royal blue-top BD vacutainer with EDTA blood collection tube (3 mL) (BD catalog no. 367777) (T989)

Acceptable: Royal blue-top BD Vacutainer Plus with EDTA blood collection tube (6 mL) (BD catalog no. 368381) (T183)

Specimen Volume: 1 mL

Collection Instructions:

1. See Metals Analysis Specimen Collection and Transport for complete instructions.

2. Send whole blood specimen in original collection tube. Do not aliquot.


Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time
Whole blood Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reference Values

< 5.0 mcg/L

Reference values apply to all ages.

Day(s) Performed

Monday through Saturday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82300

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CDOMB Cadmium Occupational Monitor, B 5609-3

 

Result ID Test Result Name Result LOINC Value
89539 Cadmium Occupational Monitor, B 5609-3

Interpretation

Normal blood cadmium is less than 5.0 mcg/L, with most results in the range of 0.5 to 2.0 mcg/L.

 

Acute toxicity will be observed when the blood level exceeds 50 mcg/L.

Clinical Reference

1. Moreau T, Orssaud G, Lellouch J, Claude JR, Juguet B, Festy B. Blood cadmium levels in a general male population with special reference to smoking. Arch Environ Health. 1983;38(3):163-167

2. Occupational Safety and Health Administration, US Department of Labor: Cadmium . Accessed December 3, 2024. Available at www.osha.gov/cadmium

3. Strathmann FG, Blum LM. Toxic elements. In: Rifai N, Chiu RWK, Young I, Burnham CD, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. Elsevier; 2023:chap 44

Report Available

1 to 3 days

Method Name

Triple Quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-MS/MS)