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Test Code 5BETH Factor V Bethesda Units, Plasma


Ordering Guidance


If type of inhibitor is unknown, order APROL / Prolonged Clot Time Profile, Plasma.



Specimen Required


Only orderable as a reflex. For more information see:

-ALUPP / Lupus Anticoagulant Profile, Plasma

-ALBLD / Bleeding Diathesis Profile, Limited, Plasma

-APROL / Prolonged Clot Time Profile, Plasma

-5INHE / Factor V Inhibitor Evaluation, Plasma


Useful For

Detecting and quantifying the presence and titer of a specific factor inhibitor directed against coagulation factor V

Method Name

-ALUPP / Lupus Anticoagulant Profile, Plasma

-ALBLD / Bleeding Diathesis Profile, Limited, Plasma

-ACBL / Bleeding Diathesis Profile, Comprehensive, Plasma

-APROL / Prolonged Clot Time Profile, Plasma

-5INHE / Factor V Inhibitor Evaluation, Plasma

 

Optical Clot-Based

Reporting Name

FV Bethesda Units, P

Specimen Type

Plasma Na Cit

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Na Cit Frozen 14 days

Reference Values

Only orderable as a reflex. For more information see:

-ALUPP / Lupus Anticoagulant Profile, Plasma

-ALBLD / Bleeding Diathesis Profile, Limited, Plasma

-ACBL / Bleeding Diathesis Profile, Comprehensive, Plasma

-APROL / Prolonged Clot Time Profile, Plasma

-5INHE / Factor V Inhibitor Evaluation, Plasma

 

≤0.5 Bethesda Units

Interpretation

An interpretive report will be provided when testing is complete.

Clinical Reference

1. Biggs R, Bidwell E. A method for the study of antihemophiliac globulin inhibitors with reference to six cases. Br J Haematol. 1959;5:379-395

2. Hoyer LW: Factor VIII inhibitors. In: Hoyer LW, eds. Progress in Clinical and Biological Research. Vol 150. R Alan Liss Inc, 1984:87-98

3. Kasper CK, Aledort L, Aronson D, et al. Proceedings: A more uniform measurement of factor VIII inhibitors. Thromb Diath Haemorrh. 1975;34(2):61

4. Kasper C, Ewing N. Acquired inhibitors of plasma coagulation factors. J Med Tech 1986;38:431-439

5. Kottke-Marchant K, ed: Laboratory Hematology Practice. Wiley Blackwell Publishing; 2012

6. Hoffman R, Benz Jr EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Elsevier; 2018

Day(s) Performed

Monday through Friday

Report Available

2 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

85335

LOINC Code Information

Test ID Test Order Name Order LOINC Value
5BETH FV Bethesda Units, P 3191-4

 

Result ID Test Result Name Result LOINC Value
607433 FV Bethesda Units, P 3191-4